Recent progress in nanomaterial-enhanced fluorescence polarization/anisotropy sensors
| dc.contributor.author | Chen, Jia | |
| dc.contributor.author | Liu, Juewen | |
| dc.contributor.author | Chen, Xingguo | |
| dc.contributor.author | Qiu, Hongdeng | |
| dc.date.accessioned | 2020-03-19T16:22:11Z | |
| dc.date.available | 2020-03-19T16:22:11Z | |
| dc.date.issued | 2019-09 | |
| dc.description | The final publication is available at Elsevier via https://doi.org/10.1016/j.cclet.2019.06.005. © 2019. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ | en |
| dc.description.abstract | As a promising signaling transduction approach, fluorescence polarization (FP)/fluorescence anisotropy (FA), provides a powerful quantitative tool for the rotational motion of fluorescently labeled molecules in chemical or biological homogeneous systems. Unlike fluorescence intensity, FP/FA is almost independent the concentration or quantum of fluorophores, but they are highly dependent on the size or molecular weight of the molecules or materials attached to fluorophores. Recently, significant progress in FP/FA was made, due to the introduction of some nanomaterials as FP/FA enhancers. The detection sensitivity is thus greatly improved by using nanomaterials as FP/FA enhancers, and nanomaterial-based FP/FA is currently used successfully in immunoassay, and analysis of protein, nucleic acid, small molecule and metal ion. Nanomaterial-based FP/FA provides a new kind of strategy to design fluorescent sensors and establishes innovative analytical methods. In this review, we summarize the scientific publications in the field of FP/FA sensor in recent five years, and first introduce the recent progress of FP/FA sensor based on nanomaterial. Subsequently, the various analytical applications of FP/FA based on nanomaterial are discussed. Finally, we provide perspectives on the current challenges and future prospects in this promising field. | en |
| dc.description.sponsorship | The authors gratefully acknowledge the financial support provided by the National Natural Science Foundation of China (No. 21822407, 21405163) and the top priority program of “One-Three-Five” Strategic Planning of Lanzhou Institute of Chemical Physics, CAS. | en |
| dc.identifier.uri | https://doi.org/10.1016/j.cclet.2019.06.005 | |
| dc.identifier.uri | http://hdl.handle.net/10012/15709 | |
| dc.language.iso | en | en |
| dc.publisher | Elsevier | en |
| dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | * |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
| dc.subject | fluorescence polarization/anisotropy | en |
| dc.subject | nanomaterials | en |
| dc.subject | sensor | en |
| dc.subject | recent progress | en |
| dc.subject | application | en |
| dc.title | Recent progress in nanomaterial-enhanced fluorescence polarization/anisotropy sensors | en |
| dc.type | Article | en |
| dcterms.bibliographicCitation | Chen J, Liu J, Chen X, Qiu H, Recent progress in nanomaterial- enhanced fluorescence polarization/anisotropy sensors, Chinese Chemical Letters (2019), https://doi.org/10.1016/j.cclet.2019.06.005 | en |
| uws.contributor.affiliation1 | Faculty of Science | en |
| uws.contributor.affiliation2 | Chemistry | en |
| uws.contributor.affiliation2 | Waterloo Institute for Nanotechnology (WIN) | en |
| uws.peerReviewStatus | Reviewed | en |
| uws.scholarLevel | Faculty | en |
| uws.typeOfResource | Text | en |
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