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Driving Adsorbed Gold Nanoparticle Assembly by Merging Lipid Gel/Fluid Interfaces

dc.contributor.authorWang, Feng
dc.contributor.authorCurry, Dennis E.
dc.contributor.authorLiu, Juewen
dc.date.accessioned2017-02-23T19:54:21Z
dc.date.available2017-02-23T19:54:21Z
dc.date.issued2015-11-23
dc.descriptionThis document is the Accepted Manuscript version of a Published Work that appeared in final form in Langmuir, copyright © American Chemical Society after peer review and technical editing by publisher. To access the final edited and published work see http://dx.doi.org/10.1021/acs.langmuir.5b03606en
dc.description.abstractSurface forces between inorganic nanoparticles and lipid bilayer is of great relevance to biophysics, medicine, and nanobiotechnology. Adsorbed nanoparticles may influence the fluidity of the underlying lipids, which may in turn influence nanoparticle assembly. Herein three types of lipids (DOPC, Tc = −20 °C; DMPC, Tc = 23 °C; and DPPC, Tc = 41 °C) are used, all with the same phosphocholine (PC) headgroup. Gold nanoparticle (AuNP) color change is monitored as a function of lipid phase transition temperature (Tc), surface ligands on AuNPs, and temperature. Liposomes with higher fluidity induce much faster aggregation of AuNPs. Aside from the kinetic aspect of faster diffusion on fluid bilayers, this faster color change is attributed to the local lipid gelation and merging of gelled regions to eliminate the interface between different lipid phases.en
dc.description.sponsorshipNatural Sciences and Engineering Research Council ||en
dc.identifier.urihttp://dx.doi.org/10.1021/acs.langmuir.5b03606
dc.identifier.urihttp://hdl.handle.net/10012/11338
dc.language.isoenen
dc.publisherAmerican Chemical Societyen
dc.subjectgold nanoparticlesen
dc.subjectlipid bilayeren
dc.titleDriving Adsorbed Gold Nanoparticle Assembly by Merging Lipid Gel/Fluid Interfacesen
dc.typeArticleen
dcterms.bibliographicCitationWang, F., Curry, D. E., & Liu, J. (2015). Driving Adsorbed Gold Nanoparticle Assembly by Merging Lipid Gel/Fluid Interfaces. Langmuir, 31(49), 13271–13274. https://doi.org/10.1021/acs.langmuir.5b03606en
uws.contributor.affiliation1Faculty of Scienceen
uws.contributor.affiliation2Waterloo Institute for Nanotechnology (WIN)en
uws.peerReviewStatusRevieweden
uws.scholarLevelFacultyen
uws.typeOfResourceTexten

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