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Boosting the oxidase mimicking activity of nanoceria by fluoride capping: rivaling protein enzymes and ultrasensitive F- detection

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dc.contributor.authorLiu, Biwu
dc.contributor.authorHuang, Zhicheng
dc.contributor.authorLiu, Juewen
dc.date.accessioned2017-04-28T16:11:58Z
dc.date.available2017-04-28T16:11:58Z
dc.date.issued2016-07-28
dc.description.abstractNanomaterial-based enzyme mimics (nanozymes) are currently a new forefront of chemical research. However, the application of nanozymes is limited by their low catalytic activity and low turnover numbers. Cerium dioxide nanoparticles (nanoceria) are among the few with oxidase activity. Herein, we report an interesting finding addressing their limitations. The oxidase activity of nanoceria is improved by over 100-fold by fluoride capping, making it more close to real oxidases. The turnover number reached 700 in 15 min, drastically improved from similar to 15 turnovers for the naked particles. The mechanism is attributed to surface charge modulation and facilitated electron transfer by F(-)capping based on zeta-potential and free radical measurements. Ultrasensitive sensing of fluoride was achieved with a detection limit of 0.64 mu M F- in water and in toothpastes, while no other tested anions can achieve the activity enhancement.en
dc.description.sponsorshipNatural Sciences and Engineering Research Council of Canada (NSERC)en
dc.identifier.urihttp://dx.doi.org/10.1039/c6nr02730j
dc.identifier.urihttp://hdl.handle.net/10012/11793
dc.language.isoenen
dc.publisherRoyal Society of Chemistryen
dc.subjectGraphene Quantum Dotsen
dc.subjectCeria Nanoparticlesen
dc.subjectGold Nanoparticlesen
dc.subjectArtificial Enzymesen
dc.subjectCatalytic-Activityen
dc.subjectGlucose Detectionen
dc.subjectPeroxidaseen
dc.subjectTio2en
dc.subjectDNAen
dc.subjectIonsen
dc.titleBoosting the oxidase mimicking activity of nanoceria by fluoride capping: rivaling protein enzymes and ultrasensitive F- detectionen
dc.typeArticleen
dcterms.bibliographicCitationLiu, B., Huang, Z., & Liu, J. (2016). Boosting the oxidase mimicking activity of nanoceria by fluoride capping: rivaling protein enzymes and ultrasensitive F- detection. Nanoscale, 8(28), 13562–13567. https://doi.org/10.1039/c6nr02730jen
uws.contributor.affiliation1Faculty of Scienceen
uws.contributor.affiliation2Chemistryen
uws.contributor.affiliation3Waterloo Institute for Nanotechnology (WIN)en
uws.peerReviewStatusRevieweden
uws.scholarLevelFacultyen
uws.typeOfResourceTexten

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