Browsing Science (Faculty of) by Subject "biosensor"
Now showing items 1-6 of 6
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Investigation of divalent metal ion detection using 17E DNAzyme Biosensor
(University of Waterloo, 2021-04-30)DNAzymes are in vitro selected oligonucleotides that can catalyze reactions, such as RNA cleavage. Most DNAzymes require metal ions as cofactors. Unlike ribozymes, which have been found in nature, all known DNAzymes are ... -
Parts-per-Million of Polyethylene Glycol as a Non-Interfering Blocking Agent for Homogeneous Biosensor Development
(American Chemical Society, 2013-11-05)Many homogeneous assays are complicated by the adsorption of probe molecules by the surface of reaction vessels, which are often made of polypropylene or polystyrene-based plastics. To solve this problem, many protein and ... -
Selected Experiments with Proteins at Solid-Liquid Interfaces
(University of Waterloo, 2008-12-12)This thesis describes a number of novel experiments contributing to the understanding of protein adsorption from both a fundamental and applied perspective. The first three papers involve the use of the localized surface ... -
Selection and characterization of an aptamer to a thiazole orange derivative for use in a fluorescence-based biosensor
(University of Waterloo, 2023-08-18)Aptamers are short single-stranded DNA or RNA sequences that have been selected in vitro to have a high binding affinity to a specific target molecule. One class of aptamers can bind to small non-fluorescent molecules to ... -
A Study of Mechanisms Governing Single Walled Carbon Nanotube Thin Film Electric Biosensors
(University of Waterloo, 2014-01-07)The successful fabrication and characterization of two chemiresistive platforms for biomolecule detection was demonstrated by this work. The Si/Silica based single walled nanotube thin film (SWNTTF) platform was developed ... -
Towards understanding of poly-guanine activated fluorescent silver nanoclusters
(Institute of Physics, 2014-03-18)It has been recently reported that the fluorescence of some DNA-templated silver nanoclusters (AgNCs) can be significantly enhanced upon by hybridizing with a partially complementary DNA containing a G-rich overhang near ...