Browsing Science (Faculty of) by Author "Sever, Lital"
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A Functional Study of the Major Histocompatibility Class I Antigen Presentation Pathway in Rainbow Trout (Oncorhynchus mykiss)
Sever, Lital (University of Waterloo, 2014-01-09)Major Histocompatibility Complex (MHC) class I receptors are glycoproteins which play a critical role in anti-viral immunity by displaying foreign peptides to cytotoxic T cell lymphocytes. The loading of high affinity ... -
Tapasin's protein interactions in the rainbow trout peptide-loading complex
Sever, Lital; Vo, Nguyen T. K.; Bols, Niels C.; Dixon, Brian (Elsevier, 2018-04-01)Major histocompatibility complex (MHC) class I receptors play a key role in the immune system by presenting non-self peptides to T cell lymphocytes. In humans, the assembly of the MHC class I with a peptide is mediated by ...