Browsing Health (Faculty of) by Author "Metherel, Adam Henry"
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Butylated hydroxytoluene can protect polyunsaturated fatty acids in dried blood spots from degradation for up to 8 weeks at room temperature
Metherel, Adam Henry; Hogg, Ryan C.; Buzikievich, Lindy M.; Stark, Ken (BioMed Central, 2013-02-20)Background: Dried blood spots (DBS) from fingertip prick blood can enable high throughput fatty acid profiling but may be prone to lipid peroxidation during storage. The use of butylated hydroxytoluene (BHT) on chromatography ... -
The Development and Assessment of Rapid Methods for Fatty Acid Profiling
Metherel, Adam Henry (University of Waterloo, 2012-08-29)Fatty acid profiling provides information on dietary intakes and an understanding of lipid metabolism. High throughput techniques such as fingertip prick (FTP) sampling has gained popularity in recent years as a simplified ... -
Omega-3 Fatty Acid Blood Biomarkers Before and After Acute Fish Oil Supplementation in Men and Women
Metherel, Adam Henry (University of Waterloo, 2007-09-17)Omega-3 fatty acids, particularly docosahexaenoic (DHA) and eicospentaenoic acid (EPA), are important mediators for cardiovascular disease, fetal/infant development, neurological disorders and inflammatory diseases. ... -
The percentage of DHA in erythrocytes can detect non-adherence to advice to increase EPA and DHA intakes
Patterson, Ashley C.; Metherel, Adam Henry; Hanning, Rhona M.; Stark, Ken (Cambridge University Press, 2014-01-28)Characterisation of long-term adherence to EPA and DHA intakes through biomarkers and dietary assessments has implications for interpreting the findings of long-term intervention studies. Adherence to dietary advice targeting ... -
Two weeks of docosahexaenoic acid (DHA) supplementation increases synthesis-secretion kinetics of n-3 polyunsaturated fatty acids compared to 8 weeks of DHA supplementation
Metherel, Adam Henry; Lacombe, R. J. Scott; Henao, Aristizabal; Morin-Rivron, Delphine; Kitson, Alex P.; Hopperton, Kathryn E.; Chalil, Daniel; Masoodi, Mojgan; Stark, Ken; Bazinet, Richard P. (Elsevier, 2018-10)Docosahexaenoic acid (DHA, 22:6n-3) must be consumed in the diet or synthesized from n-3 polyunsaturated fatty acid (PUFA) precursors. However, the effect of dietary DHA on the metabolic pathway is not fully understood. ...