Browsing Theses by Subject "site-directed mutagenesis"
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Investigations of the Natural Product Antibiotic Thiostrepton from Streptomyces azureus and Associated Mechanisms of Resistance
(University of Waterloo, 2013-03-11)The persistence and propagation of bacterial antibiotic resistance presents significant challenges to the treatment of drug resistant bacteria with current antimicrobial chemotherapies, while a dearth in replacements for ...