Browsing Theses by Subject "peptide identification"
Now showing items 1-2 of 2
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Effective Strategies for Improving Peptide Identification with Tandem Mass Spectrometry
(University of Waterloo, 2011-12-21)Tandem mass spectrometry (MS/MS) has been routinely used to identify peptides from protein mixtures in the field of proteomics. However, only about 30% to 40% of current MS/MS spectra can be identified, while many of them ... -
Improving Peptide Identification in Proteomics Data Analysis through Repeat-Preserving Decoy and Decoy-Free Retraining
(University of Waterloo, 2024-01-10)Accurately identifying peptides in proteomics is central to understanding the complexities of biological systems. Despite the advancements in proteomics data analysis, challenges related to False Discovery Rate (FDR) ...