Browsing Theses by Author "Mishra, Gyana Gourab"
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Structural characterization of f-ALS associated SOD1 mutant aggregates using conformation-specific antibodies
Mishra, Gyana Gourab (University of Waterloo, 2020-06-01)Superoxide dismutase 1 (SOD1) is a metalloenzyme ubiquitously expressed in all cells and acts as an antioxidant enzyme by catalyzing the dismutation of superoxide radicals. Several mutations in the gene encoding SOD1 are ...