Microfluidic Viscometer for Tear Films and Other Biofluids
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Date
2022-08-26
Authors
Kapadia, Wasim
Journal Title
Journal ISSN
Volume Title
Publisher
University of Waterloo
Abstract
A microfluidic viscometer platform is developed and validated for measuring microliter-volume liquid samples, such as human tear films. The microfluidic viscometer combines an optically clear acrylic chip with a hydrophobic surface coating together with a syringe pump to control the sample flow rate. Additional functionally supporting devices, including a camera and a differential pressure transducer, were used for analysis. It has been demonstrated that the microfluidic viscometer could measure the viscosities of both Newtonian and non-Newtonian liquid samples, and their relevant calculations are presented. The microfluidic viscometer has potential applications in measuring the rheological properties of biofluids for diagnostic applications.
Description
Keywords
microfluidic viscometer, tear films, microfluidic rheometer, viscosity, dry eye disease