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dc.contributor.authorCook, Richard J.
dc.contributor.authorLawless, Jerald F. 20:16:04 (GMT) 20:16:04 (GMT)
dc.descriptionThis is the peer reviewed version of the following invited article: Richard J. Cook and Jerald F. Lawless, Failure time studies with intermittent observation and losses to follow-up, Scandinavian Journal of Statistics (2020), 47(4): 1035–1063 which has been published in final form at
dc.description.abstractIn health research interest often lies in modeling a failure time process but in many cohort studies failure status is only determined at scheduled assessment times. While the assessment times may be fixed upon study entry, individuals may become lost to follow-up and miss visits subsequent to the time of loss to follow-up. We consider a three-state model to characterize a joint failure and loss to follow-up process, and use it to investigate the impact of dependent loss to follow-up on standard parametric, nonparametric, and semiparametric analysis. The effect of dependent loss to follow-up is mitigated by fitting the joint model. The performance of standard methods is studied using the asymptotic theory of misspecified models, and the finite sample performance is examined for the standard and joint analyses through simulation studies. An application to data from a youth smoking prevention study is presented for illustration.en
dc.description.sponsorshipThis work was funded by the Natural Sciences and Engineering Research Council of Canada (RGPIN 155849 and RGPIN 04207 for R.J.C. and RGPIN 8597 for J.F.L.) and the Canadian Institutes of Health Research (FRN 13887 for R.J.C.). R.J.C. is a Mathematics Faculty Research Chair at the University of Waterloo.en
dc.relation.ispartofseriesScandinavian Journal of Statistics Theory and Applications;47(4)
dc.subjectdependent censoringen
dc.subjectfailure time analysisen
dc.subjectjoint modelingen
dc.subjectloss to follow-upen
dc.subjectmodel misspecificationen
dc.titleFailure time studies with intermittent observation and losses to follow-upen
dcterms.bibliographicCitationCook, RJ, Lawless, JF. Failure time studies with intermittent observation and losses to follow‐up. Scand J Statist. 2020; 47: 1035– 1063.
uws.contributor.affiliation1Faculty of Mathematicsen
uws.contributor.affiliation2Statistics and Actuarial Scienceen

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