Show simple item record

dc.contributor.authorIeritano, Christian
dc.contributor.authorCarr, Patrick J. J.
dc.contributor.authorHasan, Moaraj
dc.contributor.authorBurt, Michael
dc.contributor.authorMarta, Rick A.
dc.contributor.authorSteinmetz, Vincent
dc.contributor.authorFillion, Eric
dc.contributor.authorMcMahon, Terrance B.
dc.contributor.authorHopkins, W. Scott 22:03:34 (GMT) 22:03:34 (GMT)
dc.description.abstractThe proton-, lithium-, and sodium-bound cysteine dimers have been investigated in a joint computational and experimental infrared multiple photon dissociation (IRMPD) study. IRMPD spectra in the 1000–2000 cm−1 region show that protonation is localized on an amine group, and that intermolecular hydrogen bonding occurs between the protonated amine and the carbonyl oxygen of the neutral Cys moiety. Alkali-bound dimers adopt structures reminiscent of those observed for the monomeric Cys·Li+ and Cys·Na+ species. Calculations of the heavier Cys2·M+ (M = K, Rb or Cs) species suggest that these are significantly less strongly bound than the lighter (M = H, Li, or Na) dimers.en
dc.description.sponsorshipWe gratefully acknowledge high performance computing support from the SHARCNET consortium of Compute Canada. We are also grateful to the Centre Laser Infrarouge dOrsay (CLIO) team and technical support staff for the valuable assistance and hospitality. The authors would like to acknowledge financial support from the Natural Sciences and Engineering Research Council (NSERC) of Canada.en
dc.publisherRoyal Society of Chemistryen
dc.titleThe structures and properties of proton- and alkali-bound cysteine dimersen
dcterms.bibliographicCitationPhys. Chem. Chem. Phys., 2016,18, 4704-4710en
uws.contributor.affiliation1Faculty of Scienceen

Files in this item


This item appears in the following Collection(s)

Show simple item record


University of Waterloo Library
200 University Avenue West
Waterloo, Ontario, Canada N2L 3G1
519 888 4883

All items in UWSpace are protected by copyright, with all rights reserved.

DSpace software

Service outages