The effects of actomyosin disruptors on the mechanical integrity of the avian crystalline lens

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Date

2015-01-27

Authors

Won, Gah-Jone
Fudge, Douglas S.
Choh, Vivian Cheng-Pei

Advisor

Journal Title

Journal ISSN

Volume Title

Publisher

Molecular Vision

Abstract

Actin and myosin within the crystalline lens maintain the structural integrity of lens fiber cells and form a hexagonal lattice cradling the posterior surface of the lens. The actomyosin network was pharmacologically disrupted to examine the effects on lenticular biomechanics and optical quality.

Description

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited, used for non-commercial purposes, and is not altered or transformed. Original Publication: Won, G.-J., Fudge, D. S., & Choh, V. (2015, January 27). The effects of actomyosin disruptors on the mechanical integrity of the avian crystalline lens. Molecular Vision, 21, 98-XX. http://www.molvis.org/molvis/v21/98/

Keywords

Actin, Myosin, Myosin light chain kinase (MLCK), Mechanical integrity, Disruptors, Crystalline lens, Force-compression, Avian, Optics, Distribution

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