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Biomimetic sensing based on chemically induced assembly of a signaling DNA aptamer on a fluid bilayer membrane

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Liu_Juewen(7).pdf (527 KB)

Date

2012-04-18

Authors

Dave, Neeshma
Liu, Juewen

Journal Title

Journal ISSN

Volume Title

Publisher

Royal Society of Chemistry

Abstract

The adenosine aptamer was split into two halves and linked to a fluid liposome surface; addition of adenosine resulted in aptamer assembly, which did not occur if the split aptamer was attached to silica nanoparticles, demonstrating the feasibility of using aptamer probes to study diffusion within lipid membranes.

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Keywords

DNA, lipid bilayer, FRET, adenosine

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Citation

URI

http://dx.doi.org/10.1039/C2CC00070A
 http://hdl.handle.net/10012/11403

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Waterloo Research
Chemistry
Waterloo Institute for Nanotechnology