Show simple item record

dc.contributor.authorMorishita, Kiyoshi
dc.contributor.authorMacLean, James L.
dc.contributor.authorLiu, Biwu
dc.contributor.authorJiang, Hui
dc.contributor.authorLiu, Juewen 20:44:57 (GMT) 20:44:57 (GMT)
dc.description.abstractFew-atom noble metal nanoclusters have attracted a lot of interest due to their potential applications in biosensor development, imaging and catalysis. DNA-templated silver nanoclusters (AgNCs) are of particular interest as different emission colors can be obtained by changing the DNA sequence. A popular analytical application is fluorescence quenching by Hg2+, where d10–d10 metallophilic interaction has often been proposed for associating Hg2+ with nanoclusters. However, it cannot explain the lack of response to other d10 ions such as Zn2+ and Cd2+. In our effort to elucidate the quenching mechanism, we studied a total of eight AgNCs prepared by different hairpin DNA sequences; they showed different sensitivity to Hg2+, and DNA with a larger cytosine loop size produced more sensitive AgNCs. In all the cases, samples strongly quenched by Hg2+ were also more easily photobleached. Light of shorter wavelengths bleached AgNCs more potently, and photobleached samples can be recovered by NaBH4. Strong fluorescence quenching was also observed with high redox potential metal ions such as Ag+, Au3+, Cu2+ and Hg2+, but not with low redox potential ions. Such metal induced quenching cannot be recovered by NaBH4. Electronic absorption and mass spectrometry studies offered further insights into the oxidation reaction. Our results correlate many important experimental observations and will fuel the further growth of this field.en
dc.description.sponsorshipUniversity of Waterloo || Canadian Foundation for Innovation || Ontario Ministry of Research & Innovation || Natural Sciences and Engineering Research Council ||en
dc.publisherRoyal Society of Chemistryen
dc.titleCorrelation of photobleaching, oxidation and metal induced fluorescence quenching of DNA-templated silver nanoclustersen
dcterms.bibliographicCitationMorishita, K., MacLean, J. L., Liu, B., Jiang, H., & Liu, J. (2013). Correlation of photobleaching, oxidation and metal induced fluorescence quenching of DNA-templated silver nanoclusters. Nanoscale, 5(7), 2840.
uws.contributor.affiliation1Faculty of Scienceen
uws.contributor.affiliation2Waterloo Institute for Nanotechnology (WIN)en

Files in this item


This item appears in the following Collection(s)

Show simple item record


University of Waterloo Library
200 University Avenue West
Waterloo, Ontario, Canada N2L 3G1
519 888 4883

All items in UWSpace are protected by copyright, with all rights reserved.

DSpace software

Service outages