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DNA adsorption by magnetic iron oxide nanoparticles and its application for arsenate detection

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Liu_Juewen(14).pdf (712.07 KB)

Date

2014-05-01

Authors

Liu, Biwu
Liu, Juewen

Journal Title

Journal ISSN

Volume Title

Publisher

Royal Society of Chemistry

Abstract

Iron oxide nanoparticles adsorb fluorescently labeled DNA oligonucleotides via the backbone phosphate and quench fluorescence. Arsenate displaces adsorbed DNA to increase fluorescence, allowing detection of arsenate down to 300 nM. This is a new way of using DNA: analyte recognition relies on its phosphate instead of the bases.

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Keywords

DNA, adsorption, nanoparticle, iron oxide, arsenate

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Citation

URI

http://dx.doi.org/10.1039/C4CC03264K
 http://hdl.handle.net/10012/11368

Collections

Waterloo Research
Chemistry
Waterloo Institute for Nanotechnology