SHORT CHIRAL SYNTHESES OF MORPHINAN AND RELATED SYSTEMS
| dc.contributor.author | Gao, Jihong | |
| dc.date.accessioned | 2008-02-20T16:32:11Z | |
| dc.date.available | 2008-02-20T16:32:11Z | |
| dc.date.issued | 2008-02-20T16:32:11Z | |
| dc.date.submitted | 2008 | |
| dc.description.abstract | Morphine and its derivatives continue to challenge the creativity of synthetic chemists. The aim of this research is to execute a short chiral synthesis of the morphinan system. Chirality is introduced via asymmetric reduction; the key step is the formation of four rings- the tetracyclic phenanthrofuran by an intramolecular Diels-Alder cycloaddition. The fifth ring was completed by three different methods, and three different pentahydrophenanthrofuran systems were obtained. | en |
| dc.identifier.uri | http://hdl.handle.net/10012/3586 | |
| dc.language.iso | en | en |
| dc.pending | false | en |
| dc.publisher | University of Waterloo | en |
| dc.subject | organic syntheses | en |
| dc.subject | morphinan system | en |
| dc.subject.program | Chemistry | en |
| dc.title | SHORT CHIRAL SYNTHESES OF MORPHINAN AND RELATED SYSTEMS | en |
| dc.type | Master Thesis | en |
| uws-etd.degree | Master of Science | en |
| uws-etd.degree.department | Chemistry | en |
| uws.peerReviewStatus | Unreviewed | en |
| uws.scholarLevel | Graduate | en |
| uws.typeOfResource | Text | en |