Multi-scale modeling of head kinematics and brain tissue response to blast exposure

dc.contributor.authorSingh, Dilaver
dc.contributor.authorCronin, Duane
dc.date.accessioned2023-03-08T15:25:11Z
dc.date.available2023-03-08T15:25:11Z
dc.date.issued2019-09-15
dc.descriptionThis preprint has not undergone peer review or any post-submission improvements or corrections. The Version of Record of this article is published in Annals of Biomedical Engineering, and is available online at https://doi.org/10.1007/s10439-018-02193-xen
dc.description.abstractInjuries resulting from blast exposure have been increasingly prevalent in recent conflicts, with a particular focus on the risk of head injury. In the current study, a multibody model (GEBOD) was used to investigate the gross kinematics resulting from blast exposure, including longer duration events such as the fall and ground impact. Additionally, detailed planar head models, in the sagittal and transverse planes, were used to model the primary blast wave interaction with the head, and resulting tissue response. For severe blast load cases (scaled distance less than 2), the translational head accelerations during primary blast were found to increase as the height-of-burst (HOB) was lowered, while the HOB was found to have no effect for cases with scaled distance greater than 2. The HOB was found to affect both the magnitude and direction of rotational accelerations, with increasing magnitudes as the HOB deviated from the height of the head. The choice of ground contact stiffness was found to greatly affect the predicted head accelerations during ground impact. For a medium soil ground material, the kinematics during ground impact were greater for scaled distances exceeding 1.5, below which the primary blast produced greater kinematic head response.en
dc.identifier.urihttps://doi.org/10.1007/s10439-018-02193-x
dc.identifier.urihttp://hdl.handle.net/10012/19189
dc.language.isoenen
dc.publisherSpringeren
dc.relation.ispartofseriesAnnals of Biomedical Engineering;
dc.subjecthead responseen
dc.subjectblasten
dc.subjectfinite element modelingen
dc.subjectmulti-scale modelingen
dc.subjectkinematicsen
dc.subjectbrain responseen
dc.titleMulti-scale modeling of head kinematics and brain tissue response to blast exposureen
dc.typeArticleen
dcterms.bibliographicCitationSingh, D., Cronin, D. Multi-Scale Modeling of Head Kinematics and Brain Tissue Response to Blast Exposure. Ann Biomed Eng 47, 1993–2004 (2019). https://doi.org/10.1007/s10439-018-02193-xen
uws.contributor.affiliation1Faculty of Engineeringen
uws.contributor.affiliation2Mechanical and Mechatronics Engineeringen
uws.peerReviewStatusRevieweden
uws.scholarLevelFacultyen
uws.typeOfResourceTexten

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