Browsing Waterloo Research by Subject "SPME"
Now showing items 1-4 of 4
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The effect of hematocrit on solid-phase microextraction
(Elsevier, 2018-02-25)Solid-phase microextraction (SPME) is an approach to sample preparation that has demonstrated its appropriateness for isolating/enriching analytes present in complex biofluids with minimum sample pre-treatment. Several ... -
Equilibrium ex vivo calibration of homogenized tissue for in vivo SPME quantitation of doxorubicin in lung tissue
(Elsevier, 2018-06-01)The fast and sensitive determination of concentrations of anticancer drugs in specific organs can improve the efficacy of chemotherapy and minimize its adverse effects. In this paper, ex vivo solid-phase microextraction ... -
A facile and fully automated on-fiber derivatization protocol for direct analysis of short-chain aliphatic amines using a matrix compatible solid-phase microextraction coating
(Elsevier, 2017-07-29)Solid-phase microextraction (SPME) analysis of short-chain aliphatic amines (C-3-C-6) in aqueous solutions was investigated using pentafluorobenzaldehyde (PFBAY) as on-fiber derivatization reagent. A standard gas generating ... -
Structure/reaction directed analysis for LC-MS based untargeted analysis
(Elsevier, 2019-03-07)In LC-MS based untargeted analysis, data is collected at the peak or ion level, although the investigated biochemistry processes occur at the compound or reaction level. To this end, the presence of redundancy peaks such ...