Browsing Chemistry by Author "Abu Mazen, Nooran"
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Mechanistic studies on the effect of membrane lipid acyl chain composition on daptomycin pore formation
Beriashvili, David; Taylor, Robert; Kralt, Braden; Abu Mazen, Nooran; Taylor, Scott D.; Palmer, Michael (Elsevier, 2018-11-01)Daptomycin is a lipopeptide antibiotic that binds and permeabilizes the cell membranes of Gram-positive bacteria. Membrane permeabilization requires both calcium and phosphatidylglycerol (PG) in the target membrane, and ...