Browsing Science (Faculty of) by Subject "PEPCK"
Now showing items 1-2 of 2
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Structural and Biochemical Insights into Previously Uncharacterized Activity of Nucleotide-Dependent Phosphoenolpyruvate Carboxykinases
(University of Waterloo, 2024-04-08)Phosphoenolpyruvate carboxykinase (PEPCK) enzymes are central to glucose metabolism, with their main role in catalyzing one of the first steps of gluconeogenesis. In addition to its primary role, PEPCK is also involved, ... -
Structural and kinetic characterization of the mechanism of regulation of phosphoenolpyruvate carboxykinase by anions
(University of Waterloo, 2019-12-19)Phosphoenolpyruvate carboxykinase (PEPCK) catalyses a reaction that is known to be thermodynamically reversible. In contrast to this thermodynamic reversibility, in eukaryotes, PEPCK is observed to primarily catalyze the ...