Browsing Science (Faculty of) by Subject "In-Vitro"

Now showing items 1-2 of 2

Assessing Physicochemical Properties of Drug Molecules via Microsolvation Measurements with Differential Mobility Spectrometry

Liu, Chang; Le Blanc, J. C. Yves; Schneider, Bradley B.; Shields, Jefry; Federico, James J.; Zhang, Hui; Stroh, Justin G.; Kauffman, Gregory W.; Kung, Daniel W.; Ieritano, Christian; Shepherdson, Evan; Verbuyst, Mitch; Melo, Luke; Hasan, Moaraj; Naser, Dalia; Janiszewski, John S.; Hopkins, W. Scott; Campbell, J. Larry (American Chemical Society, 2017-02-22)

The microsolvated state of a molecule, represented by its interactions with only a small number of solvent molecules, can play a key role in determining the observable bulk properties of the molecule. This is especially ...
Cr3+ Binding to DNA Backbone Phosphate and Bases: Slow Ligand Exchange Rates and Metal Hydrolysis

Zhou, Wenhu; Yu, Tianmeng; Vazin, Mahsa; Ding, Jinsong; Liu, Juewen (American Chemical Society, 2017-06-07)

The interaction between chromium ions and DNA is of great interest in inorganic chemistry, toxicology, and analytical chemistry. Most previous studies focused on in situ reduction of Cr(VI), producing Cr3+ for DNA binding. ...