Browsing Health (Faculty of) by Subject "sarcolipin"
Now showing items 1-4 of 4
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Does Sarcolipin Ablation Alter Deflazacort Treatment Effects in mdx Mice?
(University of Waterloo, 2017-09-27)Duchenne Muscular Dystrophy (DMD) and the murine model mdx are degenerative diseases that are characterized by the absence of the protein dystrophin causing membrane instability, calcium (Ca2+) influx, and progressive ... -
Effects of Heat Stress on HSP70, Sarcolipin, and Phospholamban Content and SERCA Function in Female and Male Rat Skeletal Muscle
(University of Waterloo, 2023-09-25)Regulation of cytosolic calcium (Ca2+) levels in muscle is vital to the health and function of muscle due to its involvement in various signaling pathways and cell functions. Sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) ... -
Effects of high-fat feeding on skeletal muscle insulin signalling in sarcolipin knockout mice
(University of Waterloo, 2010-08-26)Type II diabetes mellitus (T2DM) has been associated with the onset of diet-induced obesity, which is currently on the rise worldwide. T2DM is typically characterized by insulin resistance in peripheral tissues such as ... -
Protection against high fat diet induced obesity in mdx mice: is sarcolipin involved?
(University of Waterloo, 2018-02-15)Sarcolipin (SLN) is a 31 amino acid proteolipid and one of the regulators of sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) pumps. Previous research has shown that sarcolipin levels in muscles from wild type (WT) mice ...