Browsing Theses by Subject "blood pressure"
Now showing items 1-3 of 3
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The Effect of Spironolactone on Cerebral Blood Flow and Cognition
(University of Waterloo, 2018-03-23)Hypertension and arterial stiffness are associated with structural and functional changes in cerebral circulation and cognitive function, but based on existing evidence the effects are potentially reversible by spironolactone ... -
Endothelium-dependent vasomotor responses of hypertensive and type 2 diabetic rats: effects of sex, ageing, and therapeutic interventions
(University of Waterloo, 2009-08-26)Impaired endothelial vasomotor function is a hallmark of many chronic disease states, including essential hypertension and type 2 diabetes mellitus. Loss of the homeostatic role of the endothelium in large conduit arteries ... -
Mechanisms of over-active endothelium-derived contracting factor signaling causing common carotid artery endothelial vasomotor dysfunction in hypertension and aging
(University of Waterloo, 2011-03-09)Background and Purpose: The endothelium is a single-cell layer positioned at the blood-vascular wall interface, where in response to blood-borne signals and hemodynamic forces, endothelial cells act as central regulators ...