Browsing Theses by Subject "atomic force microscopy"
Now showing items 1-5 of 5
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Antimicrobial Peptide Daptomycin and its Inhibition by Pulmonary Surfactant: Biophysical Studies using Model Membrane Systems
(University of Waterloo, 2017-04-25)Daptomycin is a lipopeptide antibiotic that is clinically used to treat severe infections caused by Gram-positive bacteria. It is highly potent against resistant strains of bacteria such as methicillin-resistant Staphylococcus ... -
Fabrication of high aspect ratio (HAR) atomic force microscope (AFM) tips and nano-pillar arrays using pseudo-Bosch and wet etching
(University of Waterloo, 2020-08-21)This thesis is mainly focused on the research in the field of nanofabrication and application related to atomic force microscope (AFM) system. AFM tip is the most important part of AFM imaging to obtain the surface information ... -
The Interplay Between the Neuronal Plasma Membrane and Cell Signaling in Alzheimer’s Disease
(University of Waterloo, 2023-03-10)The lack of understanding in the molecular and cellular mechanisms of Alzheimer’s disease (AD) has hindered efforts towards finding treatments that effectively modify disease trajectory. Therapeutic development for AD has ... -
Open-Loop Transient Atomic Force Microscopy
(University of Waterloo, 2023-02-01)The Atomic Force Microscope (AFM) is an instrument for measuring, in fact “seeing”, phenomena at nanoscale (10^(-9) m) and all the way down to the atomic scale (<10^(-10) m). It was borne out of a need to observe physical ... -
Selected Experiments with Proteins at Solid-Liquid Interfaces
(University of Waterloo, 2008-12-12)This thesis describes a number of novel experiments contributing to the understanding of protein adsorption from both a fundamental and applied perspective. The first three papers involve the use of the localized surface ...