Browsing Theses by Subject "Glycosylation"
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Algorithms for Characterizing Peptides and Glycopeptides with Mass Spectrometry
(University of Waterloo, 2013-09-26)The emergence of tandem mass spectrometry (MS/MS) technology has significantly accelerated protein identification and quantification in proteomics. It enables high-throughput analysis of proteins and their quantities in a ... -
Supplementation Strategies for Tuning Glycosylation of Monoclonal Antibodies and Enhancing Growth in Mammalian Cell Culture by Omics Analysis
(University of Waterloo, 2018-04-17)Two fundamental objectives of bioprocess engineering are to increase productivity and improve product quality. Glycosylation is a critical and variable factor in the quality of several therapeutic proteins, particularly ...