Browsing Theses by Author "Chandani, Rabiya"
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Consequences of a lack of adult intravenous data on the prediction accuracy of pediatric physiologically based pharmacokinetic (PBPK) modeling
Chandani, Rabiya (University of Waterloo, 2015-05-22)Lack of pediatric clinical data has led to a large gap in knowledge concerning drug efficacy, safety and dosing guidelines within the pediatric population. Many pediatric off-label doses are based largely on adult studies ...