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dc.contributor.authorPanic, Ognjen
dc.date.accessioned2007-05-23 18:05:01 (GMT)
dc.date.available2007-05-23 18:05:01 (GMT)
dc.date.issued2007-05-23T18:05:01Z
dc.date.submitted2007-05-04
dc.identifier.urihttp://hdl.handle.net/10012/3087
dc.description.abstractThe biggest limitation to conventional gas chromatography (GC) is limited peak capacity, making the analysis of complex mixtures a difficult or even impossible task. Comprehensive two-dimensional gas chromatography (GC×GC) significantly increases peak capacity and resolution, improves sensitivity and generates structured 3D chromatograms. This is achieved by connecting two columns coated with different stationary phases through a special interface (modulator). The interface samples the first column effluent and periodically injects fractions of this material, as narrow injection pulses, onto the second column for further separation. Commercial instruments achieve this with cryogenic agents. Since this expensive approach permits only in-laboratory analysis, the development of simple, economical and field-capable GC×GC systems is in demand. This report summarizes the fundamentals governing GC×GC separations and a brief history of technological advances in the field. It also documents the construction of a simple interface, devoid of moving parts and cryogenic consumables, and hence highly suitable for field analysis and monitoring applications. Evaluation of the interface suggests on-par performance with more complicated cryogenic modulators. GC×GC separations of technical mixtures of fatty acid methyl esters (FAMEs), common environmental pollutants (EPA 8270), polychlorinated biphenyls (PCBs), pesticides (toxaphene), as well as selected essential oils and major distillation fractions of crude oil indicate very good performance. Most notably, the interface prototype was applied for the first ever time-resolved on-site analysis of the semivolatile organic fraction of urban air particulate matter (PM2.5).en
dc.format.extent4206653 bytes
dc.format.mimetypeapplication/pdf
dc.language.isoenen
dc.publisherUniversity of Waterlooen
dc.subjectComprehensive two-dimensional gas chromatography (GC×GC)en
dc.subjectInterface developmenten
dc.titleDevelopment of a Cost-Effective and Consumable-Free Interface for Comprehensive Two-Dimensional Gas Chromatography (GC×GC)en
dc.typeMaster Thesisen
dc.comment.hiddenIt is important that the contents of this thesis do not become available to the public, as this would jeopardize the current patent application.en
dc.pendingfalseen
dc.subject.programChemistryen
uws-etd.degree.departmentChemistryen
uws-etd.degreeMaster of Scienceen
uws.typeOfResourceTexten
uws.peerReviewStatusUnrevieweden
uws.scholarLevelGraduateen


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