Network centrality analysis of eye-gaze data in autism spectrum disorder
MetadataShow full item record
Individuals suffering from autism spectrum disorder (ASD) exhibit impaired social communication, the manifestations of which include abnormal eye contact and gaze. In this study, we first seek to characterize the spatial and temporal attributes of this atypical eye gaze. To achieve that goal, we analyze and compare eye-tracking data of ASD and typical development (TD) children. A fixation time analysis indicates that ASD children exhibit a distinct gaze pattern when looking at faces, spending significantly more time at the mouth and less at the eyes, compared with TD children. Another goal of this study is to identify an analytic approach that can better reveal differences between the face scanning patterns of ASD and TD children. Face scanning involves transitioning from one area of interest (AOI) to another and is not taken into account by the traditional fixation time analysis. Instead, we apply four network analysis approaches that measure the “importance” of a given AOI: degree centrality, betweenness centrality, closeness centrality, and eigenvector centrality. Degree centrality and eignevector centrality yield statistically significant difference in the mouth and right eye, respectively, between the ASD and TD groups, whereas betweenness centrality reveals statistically significant between-group differences in four AOIs. Closeness centrality yields statistically meaningful differences in three AOIs, but those differences are negligible. Thus, our results suggest that betweenness centrality is the most effective network analysis approach in distinguishing the eye gaze patterns between ASD and TD children.
Cite this version of the work
Mehrshad Sadria, Soroush Karimi, Anita T. Layton (2019). Network centrality analysis of eye-gaze data in autism spectrum disorder. UWSpace. http://hdl.handle.net/10012/15304
The following license files are associated with this item:
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 International
Showing items related by title, author, creator and subject.
Sloss, Craig (University of Waterloo, 2011-04-25)The character theory of the symmetric group is a powerful method of studying enu- merative questions about factorizations of permutations, which arise in areas including topology, geometry, and mathematical physics. This ...
Rishworth, Andrea (University of Waterloo, 2019-09-23)Sub-Saharan Africa (SSA) has the fastest aging population in the world. Yet its older population has the lowest life expectancy, lowest ratings of subjective wellbeing, and greatest burdens of disease in old age globally. ...
Marine redox conditions during deposition of Late Ordovician and Early Silurian organic-rich mudrocks in the Siljan ring district, central Sweden Lu, Xinze; Kendall, Brian; Stein, Holly J.; Li, Chao; Hannah, Judith L.; Gordon, Gwyneth W.; Ebbestad, Jan Ove R. (Elsevier, 2017-05-10)The Late Ordovician Period witnessed the second largest mass extinction in the Phanerozoic Eon and the Hirnantian glaciation. To infer ocean redox conditions across the Ordovician-Silurian transition, we measured the U (as ...