Now showing items 1-2 of 2

    • A Cleavable Molecular Beacon for Hg2+ Detection based on Phosphorothioate RNA Modifications 

      Huang, Po-Jung Jimmy; Wang, Feng; Liu, Juewen (American Chemical Society, 2015-06-10)
      Mercury is a highly toxic heavy metal, and detection of Hg2+ by biosensors has attracted extensive research interest in the past decade. In particular, a number of DNA-based sensing strategies have been developed. Well-known ...
    • A DNAzyme requiring two different metal ions at two distinct sites 

      Zhou, Wenhu; Zhang, Yupei; Huang, Po-Jung Jimmy; Ding, Jinsong; Liu, Juewen (Oxford University Press, 2015-12-10)
      Most previously reported RNA-cleaving DNAzymes require only a single divalent metal ion for catalysis. We recently reported a general trivalent lanthanide-dependent DNAzyme named Ce13d. This work shows that Ce13d requires ...

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