dc.contributor.author | Yang, Tianyu | |
dc.date.accessioned | 2016-09-27 20:00:06 (GMT) | |
dc.date.available | 2016-09-27 20:00:06 (GMT) | |
dc.date.issued | 2016-09-27 | |
dc.date.submitted | 2016-09-16 | |
dc.identifier.uri | http://hdl.handle.net/10012/10933 | |
dc.description.abstract | Organosulfur compounds have a wide variety of applications in pharmaceutical compounds and synthetic materials. Carbon-sulfur bonds are often found in natural and important bioactive compounds, thus the formation of C-S bonds is of high research interest. A novel method has been discovered to generate C-S bonds in tandem with C-C bond formation. This new reaction starts with aryl diynes and a sulfinate salt under copper-mediated conditions to form a new C-S bond and two new C-C bonds, which involves the functionalization of an aromatic C-H bond and a formal [3+2] cycloaddition. This thesis will discuss the reaction optimization, reaction scope and preliminary mechanistic investigations. | en |
dc.language.iso | en | en |
dc.publisher | University of Waterloo | en |
dc.subject | Copper-mediated | en |
dc.subject | C-S Bond Formation | en |
dc.subject | C(sp2)-H Functionalization | en |
dc.subject | Cascade Cyclization | en |
dc.title | Copper-mediated C-S Bond Formation and C(sp2)-H Functionalization via Cascade Cyclization | en |
dc.type | Master Thesis | en |
dc.pending | false | |
uws-etd.degree.department | Chemistry | en |
uws-etd.degree.discipline | Chemistry | en |
uws-etd.degree.grantor | University of Waterloo | en |
uws-etd.degree | Master of Science | en |
uws.contributor.advisor | Schipper, Derek | |
uws.contributor.affiliation1 | Faculty of Science | en |
uws.published.city | Waterloo | en |
uws.published.country | Canada | en |
uws.published.province | Ontario | en |
uws.typeOfResource | Text | en |
uws.peerReviewStatus | Unreviewed | en |
uws.scholarLevel | Graduate | en |