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dc.contributor.authorYang, Tianyu
dc.date.accessioned2016-09-27 20:00:06 (GMT)
dc.date.available2016-09-27 20:00:06 (GMT)
dc.date.issued2016-09-27
dc.date.submitted2016-09-16
dc.identifier.urihttp://hdl.handle.net/10012/10933
dc.description.abstractOrganosulfur compounds have a wide variety of applications in pharmaceutical compounds and synthetic materials. Carbon-sulfur bonds are often found in natural and important bioactive compounds, thus the formation of C-S bonds is of high research interest. A novel method has been discovered to generate C-S bonds in tandem with C-C bond formation. This new reaction starts with aryl diynes and a sulfinate salt under copper-mediated conditions to form a new C-S bond and two new C-C bonds, which involves the functionalization of an aromatic C-H bond and a formal [3+2] cycloaddition. This thesis will discuss the reaction optimization, reaction scope and preliminary mechanistic investigations.en
dc.language.isoenen
dc.publisherUniversity of Waterlooen
dc.subjectCopper-mediateden
dc.subjectC-S Bond Formationen
dc.subjectC(sp2)-H Functionalizationen
dc.subjectCascade Cyclizationen
dc.titleCopper-mediated C-S Bond Formation and C(sp2)-H Functionalization via Cascade Cyclizationen
dc.typeMaster Thesisen
dc.pendingfalse
uws-etd.degree.departmentChemistryen
uws-etd.degree.disciplineChemistryen
uws-etd.degree.grantorUniversity of Waterlooen
uws-etd.degreeMaster of Scienceen
uws.contributor.advisorSchipper, Derek
uws.contributor.affiliation1Faculty of Scienceen
uws.published.cityWaterlooen
uws.published.countryCanadaen
uws.published.provinceOntarioen
uws.typeOfResourceTexten
uws.peerReviewStatusUnrevieweden
uws.scholarLevelGraduateen


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