Browsing Waterloo Research by Author "Hamilton, Mark Evan"
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The characterization of γH2AX and p53 as biomarkers of genotoxic stress in a rainbow trout (Oncorhynchus mykiss) brain cell line
Hamilton, Mark Evan; Bols, Niels C.; Duncker, Bernard P. (Elsevier, 2018-06-01)Rainbow trout cell cultures were exposed to three genotoxicants and examined for effects on γH2AX and p53 levels by western blotting and on cell viability using the indicator dyes Alamar Blue (AB) for energy metabolism and ... -
VER-155008 induced Hsp70 proteins expression in fish cell cultures while impeding replication of two RNA viruses
Pham, Phuc Hoang; Sokeechand, Bibi S.H.; Hamilton, Mark Evan; Misk, Ehab; Jones, Ginny; Lee, Lucy E.J.; Lumsden, John S.; Bols, Niels C. (Elsevier, 2019-02-01)The heat-shock protein 70 (Hsp70) inhibitor, VER-155008 (VER), was explored as a potential antiviral agent for two RNA viruses important to fish aquaculture, viral hemorrhagic septicemia virus (VHSV) and infectious pancreatic ...