Now showing items 1-20 of 220

    • Automated Cataract Grading using Smartphone Images 

      Nasir zonouzi, Mona (University of Waterloo, 2021-02-02)
      A cataract is an age-related eye disease and is one of the leading ophthalmological public health problems in developed and developing countries. Early detection of cataracts is necessary to preserve sight and prevent the ...
    • Explainable AI for retinal OCT diagnosis 

      Brar, Amitojdeep Singh (University of Waterloo, 2021-01-20)
      Artificial intelligence methods such as deep learning are leading to great progress in complex tasks that are usually associated with human intelligence and experience. Deep learning models have matched if not bettered ...
    • Retinal Structure and Function in Typical Children and Young Adults 

      Albuhayzah, Hussain (University of Waterloo, 2021-01-20)
      Purpose. Children with visual impairment may be referred for ERG and OCT testing to aid in diagnosis and monitoring, particularly those with suspected retinal diseases. To establish if a result is abnormal, knowledge of ...
    • In Vitro Release of Inflammatory Cytokines from Contact Lens Materials 

      Nagaarudkumaran, Nijani (University of Waterloo, 2020-12-22)
      The upregulation of inflammatory mediators in the tear film during contact lens wear indicates that lens wear may induce an inflammatory response on the ocular surface. Previous research has investigated the relationship ...
    • Ocular Perfusion Pressure in Spaceflight-Associated Neuro-Ocular Syndrome 

      Mohiar, Yara (University of Waterloo, 2020-10-26)
      Purpose: Spaceflight associated neuro-ocular syndrome (SANS) is considered by the National Aeronautics and Space Administration (NASA) as one of the most significant barriers to long term space exploration (Larkin, 2018). ...
    • Neural modulation of the human visual cortex 

      Abuleil, Dania (University of Waterloo, 2020-09-30)
      Neuroplasticity is a phenomenon that refers to the brain’s ability to reorganize, strengthen, and form neural connections, a process that becomes increasingly more difficult with age. Gamma amino-butyric acid (GABA), the ...
    • Game play in virtual reality driving simulation involving head-mounted display and comparison to desktop display 

      Cao, Shi; Nandakumar, Krithika; Babu, Raiju; Thompson, Benjamin (Springer, 2019-11-28)
      Previous studies have reported the effect of driving simulator games on simulator sickness and eye symptoms experienced by users; however, empirical results regarding the game experience using commercial virtual reality ...
    • Deep Generative Modeling Based Retinal Image Analysis 

      Sengupta, Sourya (University of Waterloo, 2020-06-16)
      In the recent past, deep learning algorithms have been widely used in retinal image analysis (fundus and OCT) to perform tasks like segmentation and classification. But to build robust and highly efficient deep learning ...
    • Development of sports-specific classification for Paralympic skiers with visual impairment 

      Stalin, Amritha (University of Waterloo, 2020-05-28)
      Introduction: The Paralympic Games are not only a platform for athletes with disabilities to achieve their dreams, but the Games also play a major role in changing societal attitudes towards people with disabilities and ...
    • Studies on the Optimization of Neuropeptides Detection in the Human Tear Film 

      Jabeen, Asiya (University of Waterloo, 2020-05-13)
      Introduction: Dry Eye Disease (DED) stems from a disruption of the homeostasis of the tear film (TF), a thin layer of fluid covering the ocular surface. The TF consists of numerous constituents that include proteins, ...
    • Comparison of meibomian gland dropout using two infrared imaging devices 

      Wong, Stephanie; Srinivasan, Sruthi; Murphy, Paul J.; Jones, Lyndon W. (Elsevier, 2018-11-07)
      Purpose To measure the degree of meibomian gland (MG) dropout in the lower eyelid determined by analysis of images obtained from the LipiView II (LVII) and the Keratograph 5M (K5M). Methods The inferior eyelid of each ...
    • Tear evaporation rates: What does the literature tell us? 

      Wong, Stephanie; Murphy, Paul J.; Jones, Lyndon W. (Elsevier, 2017-12-24)
      Purpose A previous literature review reported tear evaporation rates (TERs) from studies conducted on rabbits and humans between 1941 and 2003. Closer examination of the presented data revealed inaccuracies in the reporting ...
    • Corneal sensitivity after ocular surgery 

      Lum, Edward; Murphy, Paul J.; Corbett, Melanie (Wolters Kluwer, 2019-07-01)
      The cornea is densely innervated with free nerve endings to provide a high level of sensitivity to foreign bodies or noxious substances. They also provide trophic support to the tissues of the cornea and facilitate their ...
    • Interaction of Tear Inflammatory Markers with Contact Lens Materials 

      Mirzapour, Parisa (University of Waterloo, 2020-01-28)
      Biomaterials are natural or synthetic materials that come into contact with biological tissue. Contact lenses are the most commonly used biomaterials, being worn by an estimated 140 million people worldwide. While contact ...
    • The blood compatibility challenge. Part 3: Material associated activation of blood cascades and cells 

      Gorbet, Maud; Sperling, Claudia; Maitz, Manfred; Siedleck, Christopher A.; Werner, Carsten; Sefton, Michael V. (Elsevier, 2019-08)
      Following protein adsorption/activation which is the first step after the contact of material surfaces and whole blood (part 2), fibrinogen is converted to fibrin and platelets become activated and assembled in the form ...
    • Topical anaesthetic use prior to rigid gas permeable contact lens fitting 

      Gill, Felicity; Murphy, Paul J.; Purslow, Christine (Elsevier, 2017-07-11)
      Purpose To investigate effect of topical anaesthetic (TA) during gas permeable (GP) contact lens (CL) fitting on subjective and objective measures of patient anxiety. Methods 47 subjects (mean ± sd age = 26.9 ± 4.9 ...
    • Effect of ambient humidity on the Cochet-Bonnet aesthesiometer 

      Lum, Edward; Murphy, Paul J. (Springer Nature, 2018-06-19)
      Purpose: The Cochet–Bonnet (COBO) aesthesiometer is the current standard in corneal sensitivity assessment. This study investigates the influence of ambient room humidity levels on the stimulus force exerted by the ...
    • Ocular impression-taking - which material is best? 

      Turner, Jennifer; Purslow, Christine; Murphy, Paul J. (Wolters Kluwer, 2019-01)
      Objectives: To assess the efficacy and effect on clinical signs of a polyvinylsiloxane (Tresident; Shütz Dental Group GmbH, Germany) compared with an irreversible hydrocolloid (Orthoprint; Zhermack SpA, Badia Polesine, ...
    • Atomic force microscopy analysis of the effect of plasma treatment on gas permeable contact lens surface topography 

      Gill, Felicity; Purslow, Christine; Murphy, Paul J. (Elsevier, 2019-02-23)
      Purpose: Using atomic force microscopy (AFM) to investigate anterior surface topography (AST) in worn and unworn, plasma surface-treated (PST) and untreated (UT) gas permeable (GP) lenses, and influence of surface topography ...
    • Overnight Corneal Swelling and Deswelling with Silicone Hydrogel Lenses 

      Moezzi, Amir Mahmoud (University of Waterloo, 2019-12-13)
      Purpose: To compare central corneal swelling (CS) after eight hours of sleep in eyes wearing 12 different silicone hydrogel (SiHy) contact lenses (CLs) and to model between-subject variability in CS and deswelling. Methods: ...

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