Browsing Chemistry by Type "Doctoral Thesis"
Now showing items 1-20 of 260
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Adnectin Solubility and Dynamics
(University of Waterloo, 2019-10-28)Rapid growth of the global market for monoclonal antibodies (mAbs) has generated considerable interest in the development of alternative molecules that facilitate rapid discovery and manufacturing, while replicating the ... -
Advanced Electrodes and Electrolytes For Long-Lived and High-Energy-Density Lithium-Sulfur Batteries
(University of Waterloo, 2017-05-16)The increasing demand on renewable but intermittent energy and the need for electrified transportation place great emphasis on energy storage. Lithium-sulfur (Li-S) batteries are promising systems due to the high theoretical ... -
Advanced Electrolyte Design for Long-Life and High-Areal-Capacity Divalent Metal Batteries
(University of Waterloo, 2024-01-22)Net-zero carbon dioxide emission demands clean renewable energy, while harnessing it requires electrochemical storage devices with high energy density, safety and affordability. To achieve decarbonization, much effort is ... -
Advanced Separation Techniques in the Analysis of Environmental Pollutants
(University of Waterloo, 2012-04-30)Recent developments in chromatographic supports and instrumentation for liquid chromatography are enabling rapid and highly efficient separations. Various analytical strategies have been recently proposed, for example the ... -
Advances in Biamperometry with Applications in Ocular Toxicology
(University of Waterloo, 2013-10-02)This thesis presents advances in biamperometry, together with applications cyclic biamperometry, in in vitro ocular cytotoxicity assessment. For the cytotoxicity/viability assessment, cultured human corneal epithelial cells ... -
Advances in Multidimensional Chromatography
(University of Waterloo, 2012-07-23)Comprehensive two-dimensional gas chromatography (GC×GC) is among the most powerful methods used to separate complex samples. Two columns of different selectivities are coupled in series through a special interface ... -
Advances in solid-phase microextraction as sample preparation method for food analysis.
(University of Waterloo, 2015-02-25)Within all steps involved in the analytical process, sample preparation is considered the most time-consuming step. Therefore, substantial efforts have focused on the search for automated sample preparation strategies that ... -
Advances in the density matrix renormalization group method for use in quantum chemistry
(University of Waterloo, 2008-05-01)Despite the success of modern quantum chemistry in predicting properties of organic molecules, the treatment of inorganic systems, which have many close lying states, remains out of quantitative reach for current methods. ... -
Advances in two-dimensional liquid chromatography
(University of Waterloo, 2022-08-26)Comprehensive two-dimensional liquid chromatography (LC×LC) offers increased peak capacity, resolution and selectivity compared to one-dimensional liquid chromatography. It is commonly accepted that the technique produces ... -
Aggregation of Amyotrophic Lateral Sclerosis-Associated Cu/Zn Superoxide Dismutase
(University of Waterloo, 2010-05-21)Amyotrophic lateral sclerosis (ALS) is a devastating, progressive, and fatal neurodegenerative disease. Despite the fact that ALS is the most common motor neuron disease in adulthood, there is no effective treatment for ... -
Algorithms for quantum molecular dynamics: from matrix product states to path integrals
(University of Waterloo, 2021-01-13)This thesis describes several novel approaches in quantum molecular dynamics for obtaining properties of molecular systems in different regimes. We investigate ground state properties of chains of linear rotors with ... -
Application of Solid Phase Microextraction for Lipid Analysis and Lipidomics
(University of Waterloo, 2016-01-29)Although the latest advancements in lipid analysis technology provide an excellent opportunity for the comprehensive study of lipidome, fulfilling the analytical requirements at the desired quality is still a major ... -
Applications of Iodonium Ylides for Donor-Acceptor Cyclopropane Synthesis
(University of Waterloo, 2021-11-30)The application of hypervalent iodine (HVI) reagents in the field of organic chemistry has emerged as a viable option for many different useful organic transformations. There have been many considerable contributions made ... -
Arborescent Copolymers: Synthesis, Properties & Metallic Nanoparticle Templating
(University of Waterloo, 2011-08-26)Graft copolymers with a dendritic (arborescent) architecture and unimolecular micelle properties have been synthesized and examined for their solution properties as well as their ability to serve as templates for the ... -
Arborescent Core–Shell–Corona Copolymers by Self-Assembly as Templates for the Preparation of Metallic Nanoparticles
(University of Waterloo, 2020-11-19)The preparation of metallic nanoparticles has been a rapidly growing field of research in recent years, because of the unique physical properties and applications of these materials. The development of applications for ... -
Arborescent Polymers From "Click" Chemistry and Other Methods
(University of Waterloo, 2014-01-02)Graft polymers with a dendritic architecture (arborescent polymers) were synthesized by “click”, anionic, and cationic grafting. Arborescent polystyrene and polybutadiene systems were synthesized by “click” coupling using ... -
Arborescent Polypeptides for Sustained Drug Delivery Applications
(University of Waterloo, 2017-08-09)This Ph.D. dissertation describes the synthesis of arborescent copolymers of generations G1 and G2 designed to serve as drug delivery nanocarriers for cancer treatment. Poly(γ-benzyl L-glutamate) (PBG) building blocks were ... -
Aspects of Polymer Chain Dynamics in Solution Studied by Fluorescence
(University of Waterloo, 2008-04-14)Several pyrene-labeled polymers and polypeptides were synthesized and their chain dynamics were characterized using steady-state and time-resolved fluorescence techniques. Firstly, four series of pyrene-labeled polystyrenes ... -
Asymmetric Synthesis using 3,3'-Disubstituted Binaphthol-modified Boronates
(University of Waterloo, 2006)A number of 3,3'-disubstituted binaphthol-modified allylboronates (<strong>2. 42a-m</strong>) were prepared from the reaction between triallylborane and the corresponding 3,3'-disubstituted binaphthols. These chiral ... -
Automated High-throughput Analysis of Multi-class Multi-residue Pharmaceutical Drugs in Animal Tissue Using Solid Phase Microextraction
(University of Waterloo, 2020-05-06)The use of veterinary pharmaceuticals in today´s intensive farming of food-producing animals is essential for the humane treatment of animals and as well as for the prevention of outbreaks of infectious diseases. Improper ...