Browsing Chemistry by Type "Article"
Now showing items 1-20 of 278
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2-Aminopurine-modified DNA homopolymers for robust and sensitive detection of mercury and silver
(Elsevier, 2017-01-15)Heavy metal detection is a key topic in analytical chemistry. DNA-based metal recognition has advanced significantly producing many specific metal ligands, such as thymine for Hg2+ and cytosine for Ag+. For practical ... -
A 30-Year Study of Impacts, Recovery, and Development of Critical Effect Sizes for Endocrine Disruption in White Sucker (Catostomus commersonii) Exposed to Bleached-Kraft Pulp Mill Effluent at Jackfish Bay, Ontario, Canada
(Frontiers, 2021-04-22)Jackfish Bay is an isolated bay on the north shore of Lake Superior, Canada that has received effluent from a large bleached-kraft pulp mill since the 1940s. Studies conducted in the late 1980s found evidence of reductions ... -
Accelerating peroxidase mimicking nanozymes using DNA
(Royal Society of Chemistry, 2015-09-07)DNA-capped iron oxide nanoparticles are nearly 10-fold more active as a peroxidase mimic for TMB oxidation than naked nanoparticles. To understand the mechanism, the effect of DNA length and sequence is systematically ... -
Accurate Determination of the Diffusion Coefficient of Proteins by Fourier Analysis with Whole Column Imaging Detection
(American Chemical Society, 2015-01-21)Analysis in the frequency domain is considered a powerful tool to elicit precise information from spectroscopic signals. In this study, the Fourier transformation technique is employed to determine the diffusion coefficient ... -
The action mechanism of daptomycin
(Elsevier, 2016-12-15)Daptomycin is a lipopeptide antibiotic produced by the soil bacterium Streptomyces roseosporus that is clinically used to treat severe infections with Gram-positive bacteria. In this review, we discuss the mode of action ... -
An Acyl-Linked Dimer of Daptomycin Is Strongly Inhibited by the Bacterial Cell Wall
(American Chemical Society, 2017-03-28)The lipopeptide antibiotic daptomycin is active against Gram-positive pathogens. It permeabilizes bacterial cell membranes, which involves the formation of membrane-associated oligomers. We here studied a dimer of daptomycin ... -
Adsorption and Desorption of DNA on Graphene Oxide Studied by Fluorescently Labeled Oligonucleotides
(American Chemical Society, 2011-03-15)Being the newest member of the carbon materials family, graphene possesses many unique physical properties resulting is a wide range of applications. Recently, it was discovered that graphene oxide can effectively adsorb ... -
Adsorption of DNA Oligonucleotides by Titanium Dioxide Nanoparticles
(American Chemical Society, 2014-01-28)Titanium dioxide (TiO2) or titania shows great promise in detoxification and drug delivery. To reach its full potential, it is important to interface TiO2 with biomolecules to harness their molecular recognition function. ... -
Adsorption of DNA onto gold nanoparticles and graphene oxide: surface science and applications
(Royal Society of Chemistry, 2012-06-28)The interaction between DNA and inorganic surfaces has attracted intense research interest, as a detailed understanding of adsorption and desorption is required for DNA microarray optimization, biosensor development, and ... -
Adsorption of Nanoceria by Phosphocholine Liposomes
(American Chemical Society, 2016-12-13)Nanoceria (CeO2 nanoparticle) possesses a number of enzyme-like activities. In particular, it scavenges reactive oxygen species based on in-vitro and in vivo antioxidation studies. An important aspect of fundamental physical ... -
Amplifying the Macromolecular Crowding Effect Using Nanoparticles
(American Chemical Society, 2012-01-11)The melting temperature (Tm) of DNA is affected not only by salt but also by the presence of high molecular weight (MW) solutes, such as polyethylene glycol (PEG), acting as a crowding agent. For short DNAs in a solution ... -
Application of Pyrene Fluorescence to the Characterization of Hydrophobically Modified Starch Nanoparticles
(American Chemical Society, 2018-06-25)Several aspects of pyrene fluorescence were applied to gain an insight into the nature of the microdomains in hydrophobically modified starch nanoparticles (HM-SNPs), prepared by reacting SNPs with propionic and hexanoic ... -
Application of solid phase microextraction for quantification of polyunstarurated fatty acids in biological fluids
(ACS, 2014)Development of a straightforward strategy for simultaneous quantitative analysis of nonesterified fatty acids (NEFA) species in biofluids is a challenging task because of the extreme complexity of fatty acid distribution ... -
Application of Solid Phase Microextraction for Quantitation of Polyunsaturated Fatty Acids in Biological Fluids
(American Chemical Society, 2014-11-17)Development of a straightforward strategy for simultaneous quantitative analysis of nonesterified fatty acids (NEFA) species in biofluids is a challenging task because of the extreme complexity of fatty acid distribution ... -
Aptamer-based biosensors for biomedical diagnostics
(Royal Society of Chemistry, 2014-06-07)Aptamers are single-stranded nucleic acids that selectively bind to target molecules. Most aptamers are obtained through a combinatorial biology technique called SELEX. Since aptamers can be isolated to bind to almost any ... -
Aptamer-Functionalized Hydrogel Microparticles for Fast Visual Detection of Mercury(II) and Adenosine
(American Chemical Society, 2012-04-25)With a low optical background, high loading capacity, and good biocompatibility, hydrogels are ideal materials for immobilization of biopolymers to develop optical biosensors. We recently immobilized mercury and lead binding ... -
Arborescent Poly(L-glutamic acid)s as Standards to Study the Dense Interior of Polypeptide Mesoglobules by Pyrene Excimer Fluorescence
(American Chemical Society, 2018-10-01)A series of arborescent poly(l-glutamic acid)s of generations 0 to 3 (PGA(GY) with Y = 0–3) were randomly labeled with 1-pyrenemethylamine to yield several Py-PGA(GY) constructs with pyrene contents ranging between 2.5 and ... -
Assembly of DNA-Functionalized Gold Nanoparticles with Gaps and Overhangs in Linker DNA
(American Chemical Society, 2011-04-28)DNA-directed assembly of gold nanoparticles (AuNPs) has been extensively studied because of its important applications in analytical chemistry, materials science, and nanomedicine. In a typical system, two DNA-functionalized ... -
Assembly of DNA-Functionalized Nanoparticles in Alcoholic Solvents Reveals Opposite Thermodynamic and Kinetic Trends for DNA Hybridization
(American Chemical Society, 2010-05-12)DNA has been a key molecule in biotechnology and nanotechnology. To date, the majority of the experiments involving DNA have been performed in aqueous solutions, which may be related to the perception that DNA hybridization ... -
Assessing Physicochemical Properties of Drug Molecules via Microsolvation Measurements with Differential Mobility Spectrometry
(American Chemical Society, 2017-02-22)The microsolvated state of a molecule, represented by its interactions with only a small number of solvent molecules, can play a key role in determining the observable bulk properties of the molecule. This is especially ...