Science (Faculty of): Recent submissions
Now showing items 1-20 of 2275
-
Pharmacokinetic modelling of clinically relevant situations in the treatment of hemophilia A and B
(University of Waterloo, 2020-04-03)Hemophilia is a congenital bleeding disorder caused by deficiency of clotting factor VIII (FVIII; hemophilia A) or IX (FIX; hemophilia B). Severe hemophilia patients have less than 1% (or 1 IU/dL) of normal factor activity, ... -
Gold nanoparticles as dehydrogenase mimicking nanozymes for estradiol degradation
(Elsevier, 2019-09)Nanozyme catalysis has been mainly focused on a few chromogenic and fluorogenic substrates, while environmentally and biologically important compounds need to be tested to advance the field. In this work, we studied oxidation ... -
Recent progress in nanomaterial-enhanced fluorescence polarization/anisotropy sensors
(Elsevier, 2019-09)As a promising signaling transduction approach, fluorescence polarization (FP)/fluorescence anisotropy (FA), provides a powerful quantitative tool for the rotational motion of fluorescently labeled molecules in chemical ... -
Bacteriophage interactions with mammalian tissue: Therapeutic applications
(Elsevier, 2019-05)The human body is a large reservoir for bacterial viruses known as bacteriophages (phages), which participate in dynamic interactions with their bacterial and human hosts that ultimately affect human health. The current ... -
Earth and environmental science immersive learning experiences using a Google Expedition Kit
(2019-07-31)How do we engage and motivate students in immersive learning experiences that are otherwise impossible (i.e. Geologic History of the Grand Canyon) or not feasible (i.e. 3D perspective of volcanoes of the world) or invisible ... -
“My pharmacist”: Creating and maintaining relationship between physicians and pharmacists in primary care settings
(Elsevier, 2020-01)Background Pharmacists and physicians are being increasingly encouraged to adopt a collaborative approach to patient care, and delivery of health services. Strong collaboration between pharmacists and physicians is known ... -
Learning about Ontario's Paleozoic Geology with Virtual Reality Google Expedition Tours
(2020-02)How well can you interpret or place into context the different geological features or rock types that are exposed along roadways, rivers, coastlines or construction sites? Here in the Department of Earth and Environmental ... -
The characterization of Dbf4 interactions and roles in genome replication and stability in Saccharomyces cerevisiae
(University of Waterloo, 2020-03-05)Dbf4-dependent kinase (DDK) is a complex composed of the Cdc7 kinase and its regulatory subunit, Dbf4. Initiation of eukaryotic DNA replication requires phosphorylation of Mcm2-7 helicase by DDK. Due to its essential role ... -
An approach to improve direct runoff estimates and reduce uncertainty in the calculated groundwater component in water balances of large lakes
(Journal of Hydrology, 2015-10-30)Groundwater is important in the overall water budget of a lake because it affects the quantity and quality of surface water and the ecological health of the lake. The water balance equation is frequently used to estimate ... -
Linking soil moisture content and carbon dioxide fluxes: From batch experiments to process-based modelling
(University of Waterloo, 2020-02-19)The emissions of carbon dioxide (CO2) from soil to the atmosphere represent a major flux within the global carbon cycle. Soil CO2 fluxes depend on environmental factors including soil moisture and oxygen, and on intrinsic ... -
Analytical Investigation of Gas Production from Methane Hydrates upon Thermal Stimulation
(University of Waterloo, 2020-02-14)In this study, analytical models are developed to investigate methane hydrate dissociation in porous media upon thermal stimulation employing wellbore heating. This work investigates how the wellbore’s external and internal ... -
The data processing pipeline for the Herschel1 - HIFI instrument
(Elsevier, 2019-04)The HIFI data processing pipeline was developed to systematically process diagnostic, calibration and astronomical observations taken with the HIFI science instrument as part of the Herschel mission. The HIFI pipeline ... -
Morphological and Multifractal Analyses of Retinal Amyloid Deposits for Staging in Alzheimer's Disease
(University of Waterloo, 2020-02-12)Dementia is a neurodegenerative condition that leads to loss of cognitive ability, typically in older adults. Alzheimer's disease (AD) is the most common cause of dementia and affects millions of people worldwide. The ... -
Rare earth elements and radiogenic strontium isotopes in carbonate minerals reveal diagenetic influence in shales and limestones in the Appalachian Basin
(Elsevier, 2019-03-30)Rare earth element (REE) signatures are often applied to interpret paleoenvironmental conditions in sedimentary basins, however the complicated diagenetic histories in dynamic depositional environments can affect interpretation ... -
Structural investigation of a new cadmium coordination compound prepared by sonochemical process: Crystal structure, Hirshfeld surface, thermal, TD-DFT and NBO analyses
(Elsevier, 2019-04)A new nanostructured cadmium complex containing a tridentate Schiff base ligand was sonochemically synthesized and characterized by XRPD, FT/IR, NMR, and single crystal X-ray crystallography. Structural data showed that ... -
Enhanced photo-stability of inverted organic solar cells via using polyethylenimine in the electron extraction layers
(Elsevier, 2019-10)The influence of using Polyethylenimine (PEI) in the electron extraction layers (EELs) on the photo-stability of inverted organic solar cells (OSCs) is investigated. Results show that introducing PEI in the commonly used ... -
Comparison of meibomian gland dropout using two infrared imaging devices
(Elsevier, 2018-11-07)Purpose To measure the degree of meibomian gland (MG) dropout in the lower eyelid determined by analysis of images obtained from the LipiView II (LVII) and the Keratograph 5M (K5M). Methods The inferior eyelid of each ... -
Tear evaporation rates: What does the literature tell us?
(Elsevier, 2017-12-24)Purpose A previous literature review reported tear evaporation rates (TERs) from studies conducted on rabbits and humans between 1941 and 2003. Closer examination of the presented data revealed inaccuracies in the reporting ... -
Corneal sensitivity after ocular surgery
(Wolters Kluwer, 2019-07-01)The cornea is densely innervated with free nerve endings to provide a high level of sensitivity to foreign bodies or noxious substances. They also provide trophic support to the tissues of the cornea and facilitate their ... -
Some Results on Qudit Quantum Error-Correction
(University of Waterloo, 2020-01-30)Quantum computing’s seemingly perpetual promise of nearness still has a few hurdles to surmount before it can become a reality. Among these hurdles is that of protection of information from random errors. A potential ...