Browsing Science (Faculty of) by Subject "Phosphoenolpyruvate carboxykinase"
Now showing items 1-3 of 3
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Functional consequences of changing structure, dynamics, and free-energy landscapes of phosphoenolpyruvate carboxykinases
(University of Waterloo, 2020-09-21)The complex relationship between structure, dynamics, and function will afford insights into the operational details of enzymes. To understand, regulate, and create enzymes, this complex nature must be comprehensively ... -
Inhibition of Phosphoenolpyruvate Carboxykinase with a 3-Mercaptopicolinic acid Analogue
(University of Waterloo, 2016-09-01)Phosphoenolpyruvate carboxykinase (PEPCK) is the metabolic enzyme that catalyzes the first committed step in gluconeogenesis and glyceroneogensis. More recently, PEPCK has been implicated in the maintenance and establishment ... -
Structural and Biochemical Insights into Previously Uncharacterized Activity of Nucleotide-Dependent Phosphoenolpyruvate Carboxykinases
(University of Waterloo, 2024-04-08)Phosphoenolpyruvate carboxykinase (PEPCK) enzymes are central to glucose metabolism, with their main role in catalyzing one of the first steps of gluconeogenesis. In addition to its primary role, PEPCK is also involved, ...