Browsing Science (Faculty of) by Author "Abu Mazen, Nooran"
Now showing items 1-2 of 2
-
Mechanistic studies on the effect of membrane lipid acyl chain composition on daptomycin pore formation
Beriashvili, David; Taylor, Robert; Kralt, Braden; Abu Mazen, Nooran; Taylor, Scott D.; Palmer, Michael (Elsevier, 2018-11-01)Daptomycin is a lipopeptide antibiotic that binds and permeabilizes the cell membranes of Gram-positive bacteria. Membrane permeabilization requires both calcium and phosphatidylglycerol (PG) in the target membrane, and ... -
Metatranscriptomic analysis of pediatric acute sinusitis: pathogen detection and host response profiling
Abu Mazen, Nooran (University of Waterloo, 2024-05-08)Acute sinusitis (AS) is the fifth leading cause of antibiotic prescriptions in children. Distinguishing bacterial AS from common viral upper respiratory infections in children is crucial to prevent unnecessary antibiotic ...