Browsing Mathematics (Faculty of) by Author "Lee, Ker-Ai"
Now showing items 1-5 of 5
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A copula model for marked point processes
Diao, Liqun; Cook, Richard J.; Lee, Ker-Ai (Springer, 2013)Many chronic diseases feature recurring clinically important events. In addition, however, there often exists a random variable which is realized upon the occurrence of each event reflecting the severity of the event, a ... -
Design of cancer trials based on progression-free survival with intermittent assessment
Zeng, Leilei; Cook, Richard J.; Lee, Ker-Ai (Wiley, 2018-03-26)Therapeutic advances in cancer mean that it is now impractical to performed phase III randomized trials evaluating experimental treatments on the basis of overall survival. As a result, the composite endpoint of progression-free ... -
Inverse Probability Weighted Estimating Equations for Randomized Trials in Transfusion Medicine
Cook, Richard J.; Lee, Ker-Ai; Cuerden, Meaghan; Cotton, Cecilia (Wiley, 2013-03-26)Thrombocytopenia is a condition characterized by extremely low platelet counts, which puts patients at elevated risk of morbidity and mortality because of bleeding. Trials in transfusion medicine are routinely designed ... -
A Multistate Model for Bivariate Interval-Censored Failure Time Data
Cook, Richard J.; Zeng, Leilei; Lee, Ker-Ai (Wiley, 2008-12)Interval-censored life-history data arise when the events of interest are only detectable at periodic assessments. When interest lies in the occurrence of two such events, bivariate-interval censored event time data are ... -
Robust Estimation of Mean Functions and Treatment Effects for Recurrent Events Under Event-Dependent Censoring and Termination: Application to Skeletal Complications in Cancer Metastatic to Bone
Cook, Richard J.; Lakhal-Chaieb, Lajmi; Lee, Ker-Ai; Lawless, Jerald F. (Taylor & Francis, 2009)In clinical trials featuring recurrent clinical events, the definition and estimation of treatment effects involves a number of interesting issues, especially when loss to follow-up may be eventrelated and when terminal ...