Browsing Public Health Sciences (School of) by Author "Razzaque, Mohammed S"
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Dysregulation of Phosphate Metabolism and Conditions Associated With Phosphate Toxicity
Brown, Ronald B; Razzaque, Mohammed S (Nature, 2015-06-03)Phosphate homeostasis is coordinated and regulated by complex cross-organ talk through delicate hormonal networks. Parathyroid hormone (PTH), secreted in response to low serum calcium, has an important role in maintaining ... -
Endocrine Regulation of Phosphate Homeostasis
Brown, Ronald B.; Razzaque, Mohammed S. (Elsevier, 2018)Phosphate, a component of nucleic acids, DNA and RNA, is incorporated in the structure of phospholipids in cell membranes, and is involved in many biological functions such as cell signaling, energy metabolism, and bone ... -
Phosphate toxicity and tumorigenesis
Brown, Ronald B.; Razzaque, Mohammed S. (Elsevier, 2018-04-01)In this article, we briefly summarized evidence that cellular phosphate burden from phosphate toxicity is a pathophysiological determinant of cancer cell growth. Tumor cells express more phosphate cotransporters and store ... -
Vitamin D supplements: Magic pill or overkill?
Brown, Ronald B; Al Anouti, Fatme; Razzaque, Mohammed S (Bangladesh Journals Online, 2016-07-25)Vitamin D is a multifunctional micronutrient that exerts hormonal effects on many organs of the body. 1,25 dihydroxyvitamin D is the active metabolite of vitamin D, formed by dual hydroxylation in the liver and kidney.