Browsing Health (Faculty of) by Author "Gamu, Daniel"
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Deletion of Sarco(endo)plasmic Reticulum Ca2+-ATPase Regulatory Proteins: Impacts on Energy Metabolism and Obesity
Gamu, Daniel (University of Waterloo, 2017-11-28)The sarco(endo)plasmic reticulum (SR) Ca2+-ATPase (SERCA) is responsible for maintaining low cytosolic [Ca2+] through the ATP-dependent pumping of Ca2+ ions from the cytosol into the SR lumen. SERCA activity has the ... -
Examination of Voluntary Wheel Running and Skeletal Muscle Metabolism in the Sarcolipin Knock-Out Mouse
Gamu, Daniel (University of Waterloo, 2012-01-19)Sarcolipin (SLN) is a small sarcoplasmic reticulum (SR) integral membrane protein that regulates the SR Ca2+-ATPase (SERCA). Previous studies indicate that the functional interaction between SLN and SERCA is thermogenic ...