Browsing Theses by Subject "fatty acids"
Now showing items 1-7 of 7
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The Development and Assessment of Rapid Methods for Fatty Acid Profiling
(University of Waterloo, 2012-08-29)Fatty acid profiling provides information on dietary intakes and an understanding of lipid metabolism. High throughput techniques such as fingertip prick (FTP) sampling has gained popularity in recent years as a simplified ... -
Fatty Acyl-Specific Macrolipidomics and Microlipidomics for Nutritional Research
(University of Waterloo, 2019-08-13)The field of lipidomics can further our understanding of the biochemical processes of human health and disease. Generally, lipidomics methods utilize high-performance liquid chromatography (HPLC) for lipid separation, ... -
Identification and characterization of a novel microsomal enzyme involved in cardiolipin synthesis and remodeling
(University of Waterloo, 2018-05-17)Cardiolipin (CL) is a specialized dimeric phospholipid predominantly found in the inner mitochondrial membrane in eukaryotes. Following de novo synthesis, the acyl chains of CL are remodeled in a manner that is tissue- and ... -
Investigating the Interactions of Fatty Acids, Amyloid Beta & SARS-CoV-2 Spike Protein Fragment
(University of Waterloo, 2023-05-16)There is no cure for Alzheimer’s disease (AD), and the negative implications of having AD were further exacerbated in recent years, as patients with dementia are at the highest risk for mortality upon contracting COVID-19. ... -
Optimizing protein S-acylation detection in autophagy
(University of Waterloo, 2021-06-04)S-acylation, sometimes referred to as S-palmitoylation or simply palmitoylation, is a posttranslational protein modification involving the covalent addition of a fatty acid to cysteine residues. Since the first characterization ... -
Solid phase microextraction: a versatile technique for lipid analysis
(University of Waterloo, 2023-04-26)Extensive multidisciplinary research and improvements to instrumentation and workflows are continuously enabling new insights into the role of lipids in health and disease. As with other metabolites, the accurate analysis ... -
Variation in fish fatty acid concentrations among lakes in the Dehcho region of the Northwest Territories
(University of Waterloo, 2020-12-22)Background: In the subarctic Dehcho region of the Northwest Territories, many remote communities rely on traditional foods, including fish, to supplement more expensive store-bought options. Fish are an excellent source ...