Browsing University of Waterloo by Subject "enzyme kinetics"
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Biochemical and Microbiological Investigations of Inhibitors for β-Lactamases from Human Pathogenic Bacteria
(University of Waterloo, 2019-04-30)The majority of antibiotics prescribed for treatment of bacterial infections are β-lactam antibiotics. Resistance to these has evolved in a few different ways, notably by regulating permeability and by the expression of ... -
In vitro studies of NOS inhibitors using purified human NOS isozymes
(University of Waterloo, 2017-12-18)Endogenous nitric oxide (NO) is derived from L-arginine via a chemical reaction catalyzed by nitric oxide synthases (NOS). Three NOS isozymes are found in humans: neuronal NOS (nNOS), endothelial NOS (eNOS) and inducible ...