Akhlagh Moayed, AlirezaHariri, SepidehChoh, Vivian Cheng-PeiBizheva, Kostadinka2017-02-222017-02-222012-02-08https://doi.org/10.1117/1.JBO.17.1.016011http://hdl.handle.net/10012/11329Akhlagh Moayed, A., Hariri, S., Choh, V., & Bizheva, K. (2012). Correlation of visually evoked intrinsic optical signals and electroretinograms recorded from chicken retina with a combined functional optical coherence tomography and electroretinography system. Journal of Biomedical Optics, 17(1), 0160111–0160115. Copyright 2012 Society of Photo Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited. http://dx.doi.org/10.1117/1.JBO.17.1.016011Visually evoked fast intrinsic optical signals (IOSs) were recorded for the first time in vivo from all layers of healthy chicken retina by using a combined functional optical coherence tomography (fOCT) and electroretinography (ERG) system. The fast IOSs were observed to develop within ∼5  ms from the on-set of the visual stimulus, whereas slow IOSs were measured up to 1 s later. The visually evoked IOSs and ERG traces were recorded simultaneously, and a clear correlation was observed between them. The ability to measure visually evoked fast IOSs non-invasively and in vivo from individual retinal layers could significantly improve the understanding of the complex communication between different retinal cell types in healthy and diseased retinas.enBiomedical Optics & Medical ImagingTomographyElectronic Imaging & Signal ProcessingSignal ProcessingArticle