Piri, ZahraMoradi–Shoeili, ZeinabAssoud, Abdeljalil2018-10-112018-10-112019-01-01https://dx.doi.org/10.1016/j.ica.2018.09.054http://hdl.handle.net/10012/13987The final publication is available at Elsevier via https://dx.doi.org/10.1016/j.ica.2018.09.054 © 2019. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/Using ultrasonic irradiations, three new complexes of type [ZnL2].CH3CN, [NiLCl] and [CoL2] (where L is 2-acetylpyridine-4N-p-chlorophenylthiosemicarbazone ligand) have been prepared and investigated using various spectroscopic methods. Crystal structures of ZnL2 and NiLCl complexes displayed distorted octahedral and square-planar coordination geometry around the central metal, respectively. The UV-visible and mass spectroscopic analysis revealed 1:2 (metal:ligand) stoichiometry for Co(II) complex. The synthesized complexes have been used as precursors for preparing their corresponding nano-sized metal oxides via thermal decomposition. The nanostructures of metal oxides were characterized by scanning electron microscope (SEM), energy dispersive X-ray (EDX), X–ray diffraction (XRD) and Fourier transform infrared (FT–IR). The in vitro antibacterial activity of thiosemicarbazone complexes and their corresponding nano-sized metal oxides were studied against a series of gram positive and gram negative bacteria, using the zone inhibition methods. While NiLCl complex was shown to possess more antimicrobial activity than its nano-sized metal oxide, the prepared nano-sized zinc and cobalt oxides have shown the highest activity.enAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/AntibacterialNano-sized metal oxideSonochemical synthesisThiosemicarbazoneTransition metal complexesArticle