Lato, Sabrina2023-09-152023-09-152023-09-152023-07-27http://hdl.handle.net/10012/19866This thesis is about distance-biregular graphs– when they exist, what algebraic and structural properties they have, and how they arise in extremal problems. We develop a set of necessary conditions for a distance-biregular graph to exist. Using these conditions and a computer, we develop tables of possible parameter sets for distancebiregular graphs. We extend results of Fiol, Garriga, and Yebra characterizing distance-regular graphs to characterizations of distance-biregular graphs, and highlight some new results using these characterizations. We also extend the spectral Moore bounds of Cioaba et al. to semiregular bipartite graphs, and show that distance-biregular graphs arise as extremal examples of graphs meeting the spectral Moore bound.endistance-biregular graphsorthogonal polynomialsspectral Moore boundsspectral excessfeasiblecoherent configurationDistance-Biregular Graphs and Orthogonal PolynomialsDoctoral Thesis