Lin, Wei Ting DavidHuang, Po-Jung JimmyPautler, RachelLiu, Juewen2017-02-272017-02-272014-07-18http://dx.doi.org/10.1039/C4CC05551Ahttp://hdl.handle.net/10012/11369Using sensitized Tb3+ luminescence spectroscopy as a tool, binding of 14 lanthanides to a lanthanide-dependent DNAzyme is studied, where the binding affinity is symmetric across the series and the tightest binding occurs with Nd3+ and Ho3+. This trend does not correlate with DNAzyme activity, suggesting that metal binding may not be the rate-limiting step of the DNAzyme catalysis.enDNADNAzymesmetal bindingCleavageArticle