Now showing items 1-4 of 4
The effect of hematocrit on solid-phase microextraction
Solid-phase microextraction (SPME) is an approach to sample preparation that has demonstrated its appropriateness for isolating/enriching analytes present in complex biofluids with minimum sample pre-treatment. Several ...
A facile and fully automated on-fiber derivatization protocol for direct analysis of short-chain aliphatic amines using a matrix compatible solid-phase microextraction coating
Solid-phase microextraction (SPME) analysis of short-chain aliphatic amines (C-3-C-6) in aqueous solutions was investigated using pentafluorobenzaldehyde (PFBAY) as on-fiber derivatization reagent. A standard gas generating ...
Equilibrium ex vivo calibration of homogenized tissue for in vivo SPME quantitation of doxorubicin in lung tissue
The fast and sensitive determination of concentrations of anticancer drugs in specific organs can improve the efficacy of chemotherapy and minimize its adverse effects. In this paper, ex vivo solid-phase microextraction ...
Structure/reaction directed analysis for LC-MS based untargeted analysis
In LC-MS based untargeted analysis, data is collected at the peak or ion level, although the investigated biochemistry processes occur at the compound or reaction level. To this end, the presence of redundancy peaks such ...