Browsing Waterloo Research by Subject "biosensors"
Now showing items 1-7 of 7
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A Comprehensive Screen of Metal Oxide Nanoparticles for DNA Adsorption, Fluorescence Quenching, and Anion Discrimination
(American Chemical Society, 2015-10-22)Although DNA has been quite successful in metal cation detection, anion detectioin remains challenging because of the charge repulsion. Metal oxides represent a very important class of materials, and different oxides might ... -
Dissecting the effect of anions on Hg2+ detection using a FRET based DNA probe
(Royal Society of Chemistry, 2012-08-07)Many biosensors have been developed to detect Hg2+ using thymine-rich DNA. While sensor response to various cations is often studied to demonstrate selectivity, the effect of anions has been largely overlooked. Anions may ... -
DNA stabilized silver nanoclusters for ratiometric and visual detection of Hg2+ and its immobilization in hydrogels
(Elsevier, 2013-04-11)DNA oligomers are particularly interesting templates for making silver nanoclusters (AgNCs) as different emission colors can be obtained by varying the DNA sequence. Many AgNCs have been used as Hg2+ sensors since Hg2+ ... -
A droplet-based microfluidic platform for rapid immobilization of quantum dots on individual magnetic microbeads
(Springer Nature, 2018-06-01)Quantum dots (QDs) provide opportunities for the development of bioassays, biosensors, and drug delivery strategies. Decoration of the surface of QDs offers unique functions such as resistance to non-specific adsorption, ... -
Functional nucleic acids for detecting bacteria
(De Gruyter, 2013-01-31)Bacterial infection represents one of the leading causes of disease and death, and as such, bacterial detection is an important step in managing infectious diseases. The current protocol requires growing cell cultures, ... -
Sensing guanine and its derivatives: From molecular recognition to applications
(Elsevier, 2020-11)Guanine plays an indispensable role in building nucleic acids, and its derivatives take part in various cellular functions such as regulating biological reactions and signal transduction. Monitoring the levels of guanine ... -
Synergistic pH effect for reversible shuttling aptamer-based biosensors between graphene oxide and target molecules
(Royal Society of Chemistry, 2011-06-07)DNA aptamers are known to desorb from graphene oxide (GO) surface in the presence of target molecules. We demonstrate herein that the binding equilibrium can be shifted by simply tuning the solution pH. At lower pH, the ...