Browsing Waterloo Research by Subject "Domain"
Now showing items 1-3 of 3
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Dynamics of Nitric Oxide Synthase–Calmodulin Interactions at Physiological Calcium Concentrations
(American Chemical Society, 2015-03-24)The intracellular Ca2+ concentration is an important regulator of many cellular functions. The small acidic protein calmodulin (CaM) serves as a Ca2+ sensor and control element for many enzymes. Nitric oxide synthase (NOS) ... -
Solution Structure of Calmodulin Bound to the Target Peptide of Endothelial Nitric Oxide Synthase Phosphorylated at Thr495
(American Chemical Society, 2014-03-04)Nitric oxide synthase (NOS) plays a major role in a number of key physiological and pathological processes, and it is important to understand how this enzyme is regulated. The small acidic calcium binding protein, calmodulin ... -
Structural Consequences of Calmodulin EF Hand Mutations
(American Chemical Society, 2017-02-21)Calmodulin (CaM) is a cytosolic Ca2+-binding protein that serves as a control element for many enzymes. It consists of two globular domains, each containing two EF hand pairs capable of binding Ca2+, joined by a flexible ...